Yasushi Ikarashi Selected Research

Yi-Gan San

1/2021	Gender differences in plasma pharmacokinetics and hepatic metabolism of geissoschizine methyl ether from Uncaria hook in rats.
1/2020	Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis.
12/2018	Basic Study of Drug-Drug Interaction between Memantine and the Traditional Japanese Kampo Medicine Yokukansan.
1/2018	Serotonin Receptor Binding Characteristics of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook.
1/2017	Multiple Psychopharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan, and the Brain Regions it Affects.
1/2017	Cellular Pharmacological Effects of the Traditional Japanese Kampo Medicine Yokukansan on Brain Cells.
5/2015	Yokukansan, a traditional Japanese medicine, decreases head-twitch behaviors and serotonin 2A receptors in the prefrontal cortex of isolation-stressed mice.
1/2015	Protective effects of glycycoumarin and procyanidin B1, active components of traditional Japanese medicine yokukansan, on amyloid β oligomer-induced neuronal death.
1/2014	Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-.
8/2013	Glycyrrhiza and Uncaria Hook contribute to protective effect of traditional Japanese medicine yokukansan against amyloid β oligomer-induced neuronal death.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yasushi Ikarashi Research Topics

Disease

9	Dementia (Dementias) 01/2020 - 10/2009
7	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021 - 09/2009
5	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 02/2009
4	Hot Flashes 10/2009 - 11/2003
2	Parkinson Disease (Parkinson's Disease) 01/2021 - 01/2009
2	Learning Disabilities (Learning Disability) 04/2011 - 10/2010
2	Thiamine Deficiency 10/2010 - 01/2010
2	Prostatic Neoplasms (Prostate Cancer) 11/2004 - 11/2003
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017
1	Dyskinesias (Dyskinesia) 01/2016
1	Hallucinations (Hallucination) 05/2015
1	Pheochromocytoma 01/2014
1	Tardive Dyskinesia 12/2012
1	Synucleinopathies 01/2009
1	Hypoxia (Hypoxemia) 03/2007
1	Breast Neoplasms (Breast Cancer) 03/2005
1	Frontotemporal Dementia (Semantic Dementia) 02/2005
1	Carcinoma (Carcinomatosis) 11/2004
1	Amyloidosis 04/2004
1	Hypersensitivity (Allergy) 11/2003

Drug/Important Bio-Agent (IBA)

19	Yi-Gan SanIBA 01/2021 - 02/2009
3	geissoschizineIBA 01/2021 - 01/2018
3	Ether (Diethyl Ether)IBA 01/2021 - 01/2018
2	Indole AlkaloidsIBA 01/2021 - 01/2018
2	Pharmaceutical PreparationsIBA 12/2018 - 05/2015
2	Glutamic Acid (Glutamate)FDA Link 01/2014 - 01/2010
2	Proteins (Proteins, Gene)FDA Link 04/2011 - 06/2009
2	Amyloid beta-PeptidesIBA 06/2009 - 04/2004
2	Cholinergic Agents (Cholinergics)IBA 03/2007 - 04/2004
2	Acetylcholine (Acetylcholine Chloride)FDA Link 03/2007 - 04/2004
2	Hormones (Hormone)IBA 11/2004 - 11/2003
2	Calcitonin Gene-Related PeptideIBA 11/2004 - 11/2003
1	AntioxidantsIBA 01/2021
1	Neuroprotective AgentsIBA 01/2021
1	AlkaloidsIBA 01/2021
1	Memantine (Namenda)FDA Link 12/2018
1	Levodopa (L Dopa)FDA LinkGeneric 01/2016
1	BenserazideIBA 01/2016
1	Hallucinogens (Psychedelics)IBA 05/2015
1	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 05/2015
1	Cystine (L-Cystine)IBA 01/2014
1	AntiportersIBA 01/2014
1	haloperidol decanoate FDA LinkGeneric 12/2012
1	Haloperidol (Haldol)FDA LinkGeneric 12/2012
1	Donepezil (Aricept)FDA LinkGeneric 04/2011
1	Amyloid (Amyloid Fibrils)IBA 04/2011
1	Glycyrrhetinic Acid (Po 12)IBA 01/2010
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2010
1	Selective Estrogen Receptor Modulators (SERM)IBA 10/2009
1	Thiamine (Aneurin)FDA Link 10/2009
1	alpha-SynucleinIBA 01/2009
1	sinapinic acidIBA 03/2007
1	Scopolamine (Hyoscine)FDA Link 03/2007
1	Potassium CyanideIBA 03/2007
1	3,6'-disinapoylsucroseIBA 03/2007
1	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 03/2007
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 03/2005
1	Estrogens (Estrogen)FDA Link 03/2005
1	keishibukuryoganIBA 03/2005
1	Prion ProteinsIBA 02/2005
1	AndrogensIBA 11/2004
1	Testosterone (Sustanon)FDA Link 11/2004
1	Progesterone FDA LinkGeneric 11/2004
1	Estradiol (Delestrogen)FDA LinkGeneric 11/2004
1	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 11/2003

Therapy/Procedure

9	Kampo Medicine (Kampo) 01/2021 - 08/2013
1	Estrogen Replacement Therapy 10/2009
1	Ligation 03/2007
1	Decompression 03/2007
1	Ovariectomy (Oophorectomy) 03/2005
1	Therapeutics 11/2004
1	Castration 11/2003